Analysis of Mitochondrial Metabolism in Cancer Cells by Combining Hyperpolarization and Isotopomer Analysis
نویسندگان
چکیده
C. E. Harrison, R. J. DeBerardinis, A. K. Jindal, C. Yang, A. D. Sherry, and C. R. Malloy Advanced Imaging Research Center, UT Southwestern, Dallas, Texas, United States, Physics, UT Dallas, Richardson, Texas, United States, Pediatrics, UT Southwestern, Dallas, Texas, United States, McDermott Center for Human Growth and Development, UT Southwestern, Dallas, Texas, United States, Chemistry, UT Dallas, Richardson, Texas, United States, Veterans Affairs, NorthTexas Health Care System, Dallas, Texas, United States
منابع مشابه
Investigation on metabolism of cisplatin resistant ovarian cancer using a genome scale metabolic model and microarray data
Objective(s): Many cancer cells show significant resistance to drugs that kill drug sensitive cancer cells and non-tumor cells and such resistance might be a consequence of the difference in metabolism. Therefore, studying the metabolism of drug resistant cancer cells and comparison with drug sensitive and normal cell lines is the objective of this research. Material and Methods:Metabolism of c...
متن کاملInduction of Apoptosis by extract of Persian Gulf Marine Mollusk, Turbo coronatus through the ROS-Mediated Mitochondrial Targeting on Human Epithelial Ovarian Cancer Cells
Despite recent improvements in treatment, ovarian cancer is still the leading cause of death from gynaecological malignancies. Today, marine mollusks are considered as natural source of new biologically and pharmacologically active compounds by scientists and the pharmaceutical industries. The aim of this study is to investigate the selective apoptotic effects of Turbo coronatus crude extract f...
متن کاملInduction of Apoptosis by extract of Persian Gulf Marine Mollusk, Turbo coronatus through the ROS-Mediated Mitochondrial Targeting on Human Epithelial Ovarian Cancer Cells
Despite recent improvements in treatment, ovarian cancer is still the leading cause of death from gynaecological malignancies. Today, marine mollusks are considered as natural source of new biologically and pharmacologically active compounds by scientists and the pharmaceutical industries. The aim of this study is to investigate the selective apoptotic effects of Turbo coronatus crude extract f...
متن کاملMitochondrial apoptosis induced by Chamaemelum nobile extract in breast cancer cells
Chamaemelum nobile (Asteraceae) commonly known as 'Roman chamomile' is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. The present study was carried out to investigate the anticancer as well as apoptotic activity of ethyl acetate fraction of C. nobile on different cancerous cell lines. The cells were treated with varying concent...
متن کاملMitochondrial apoptosis induced by Chamaemelum nobile extract in breast cancer cells
Chamaemelum nobile (Asteraceae) commonly known as 'Roman chamomile' is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. The present study was carried out to investigate the anticancer as well as apoptotic activity of ethyl acetate fraction of C. nobile on different cancerous cell lines. The cells were treated with varying concent...
متن کامل